Clinical Article: The Bioidentical Hormone Debate

Kent Holtorf, MD,  is an expert in natural bioidentical hormone replacement and optimization for women and men, endocrinology, thyroid dysfunction (difficult thyroid cases), fatigue syndromes, adrenal insufficiency, growth hormone replacement, chronic fatigue syndrome, fibromyalgia, chronic infections and multiple endocrine dysfunction.

In this article: “Are Bioidentical Hormones (Estradiol, Estriol, and Progesterone) Safer or More Efficacious than Commonly Used Synthetic Versions in Hormone Replacement Therapy?”  This paper aimed to evaluate the evidence comparing bioidentical hormones, with the commonly used nonbioidentical versions of HRT for clinical efficacy, physiologic actions on breast tissue, and risks for breast cancer and cardiovascular disease.

In conclusion:
A thorough review of the medical literature supports the claim that bioidentical hormones have some distinctly different, often opposite, physiological effects to those of their synthetic counterparts.  With respect to the risk of breast cancer, heart disease, heart attack, and stroke, substantial scientific and medical evidence demonstrates that bioidentical hormones are safer and more efficacious forms of HRT than commonly used synthetic versions.  More randomized control trials of substantial size and length will be needed to further delineate these differences.

For the full 13 page study: Click Here